MEYD-941 Kanae Yumemi, a married woman investigator, is injected with a sex-reversing aphrodisiac and becomes a wreck.

Kanae was a dominatrix at an SM club, but her mental strength earned her a scouting by a special agency. Her mission is to eradicate an ecstasy drug manufacturing organization. She gets captured and injected with a drug that reverses sexual tendencies, turning her into a masochist. The beautiful female investigator falls into depravity as the case involves a business-world boss and her own husband.